Acyl bromides
Medchemexpress LLC Pinaverium bromide | 53251-94-8 | 99.7% | 591.42 | 10 MG
Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract. It effectively relieves pain, diarrhea, and intestinal discomfort, providing good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients.
- Inhibits GM-CSF or CXCL1/CXCL2 induced neutrophil migration and ROS production.
- Inhibits GM-CSF induced expression of cytokines (IL-1β, IL-6, and TNF-α) in primed neutrophils.
- Inhibits the contractile response to ACh or KCl in colonic circular muscle.
- Inhibits excessive systemic inflammation in Lipopolysaccharide-induced mice.
Medchemexpress LLC Mepenzolate bromide | 76-90-4 | 99.9% | 420.34 | 100 MG
Mepenzolate bromide is an orally administered muscarinic receptor antagonist with Kis of 0.68 and 2.6 nM for hM2R and hM3R, respectively. It can be used to suppress gastrointestinal hypermotility associated with irritable bowel syndrome. Mepenzolate bromide is also a GPR109A inhibitor.
- Muscarinic receptor antagonist
- GPR109A inhibitor
- Exerts anti-inflammatory effect via a muscarinic receptor-independent mechanism
- Bronchodilatory effect via a muscarinic receptor-dependent mechanism
- Subtype-non-specific muscarinic antagonist
- Beneficial effects in a mouse model of chronic obstructive pulmonary disease (COPD)
Selleck Chemical LLC Methylbenactyzine Bromide S4623-25mg
Methylbenactyzine Bromide (Gastrimade Noinarin Paragone Semulgin) is a kind of muscarinic cholinergic receptor antagonist with antispasmodic activity
Selleck Chemical LLC Sepantronium Bromide (YM155) S1130-25mg
Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0 54 nM in HeLa-SURP-luc and CHO-SV40-luc cells does not significantly inhibit SV40 promoter activity but is observed to slightly inhibit the interaction of Survivin with XIAP YM155 down-regulates survivin and XIAP modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells Phase 2
Medchemexpress LLC Cimetropium Bromide | 51598-60-8 | 438.36 | 5 MG
Cimetropium Bromide (DA-3177) is a mAChR antagonist used for the long-term treatment of irritable bowel syndrome.
Medchemexpress LLC 1,3,5-Tri-o-benzoyl-a-d-ribofuranose | 22224-41-5 | 99.75% | 462.45 | 1 ML
1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog, which exhibits broad antitumor activity by targeting indolent lymphoid malignancies. Its anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis.
- Purine nucleoside analog
- Broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
Medchemexpress LLC N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine | 67219-55-0 | 98.9% | 633.69 | 5 G
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine, also known as 5'-O-DMT-N4-Bz-dC, is a compound that can be used for the synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. It serves as a useful tool for probing enzyme-catalyzed cleavage processes in DNA.
- Used for synthesis of oligodeoxynucleotides.
- Useful tool for probing enzyme-catalyzed cleavage processes in DNA.
Medchemexpress LLC N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine | 64325-78-6 | 98.0% | 657.71 | 1 ML
N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine serves as an intermediate in various chemical processes. It is intended for research use only and is not sold to patients.
- Used as a chemical intermediate.
- High purity of 98.0%.
- Available in different forms including solid and a 10 mM solution in DMSO.
- Detailed solubility information and stock solution preparation guidance provided.
- Comprehensive documentation including Data Sheet, COA, SDS, and Handling Instructions.
Medchemexpress LLC 1,3,5-Tri-O-benzoyl-a-D-ribofuranose | 22224-41-5 | 99.8% | 462.45 | 50 G
1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs exhibit broad antitumor activity, specifically targeting indolent lymphoid malignancies.
- Inhibition of DNA synthesis
- Induction of apoptosis
Apexbio Technology LLC Rocuronium Bromide 119302-91-9 10mM (in 1mL DMSO)
Rocuronium Bromide (CAS 119302-91-9) is an aminosteroid compound that functions as a non-depolarizing neuromuscular blocking agent It acts by competitively antagonizing nicotinic acetylcholine receptors at the neuromuscular junction thereby inhibiting acetylcholine-induced depolarization and subsequent muscle contraction In research settings Rocuronium Bromide is utilized to investigate neuromuscular transmission and to model pharmacological blockade of skeletal muscle activity supporting studies in anesthesia muscle physiology and synaptic transmission mechanisms
Cayman Chemical N4-benzoyl-2-DeoxycytIdIn 5g
A building block; has been used in the synthesis of nucleosides and nucleotides with anticancer activity, as well as oligonucleotides
Medchemexpress LLC Pinaverium bromide | 53251-94-8 | 99.7% | 591.42 | 5.9 MG
Pinaverium bromide is an L-type calcium channel blocker that selectively targets the gastrointestinal tract. It is effective in relieving pain, diarrhea, and intestinal discomfort, providing therapeutic benefits for patients with Irritable Bowel Syndrome (IBS) without significant adverse effects.
- L-type calcium channel blocker
- Gastrointestinal selectivity
- Symptom relief for pain, diarrhea, and intestinal discomfort
- Therapeutic for Irritable Bowel Syndrome patients
- Favorable safety profile