Acyl bromides
Medchemexpress LLC N4-Benzoyl-2 -O-meth 250mg
N4-Benzoyl-2 -O-methylcytidine is a natural cytidine nucleoside analog Cytidine analogs have the mechanism of inhibiting DNA methyltransferase (such as Zebularine (HY-13420)) and have potential antimetabolite and antitumor activities[1][2]
Medchemexpress LLC 1,3,5-Tri-O-benzoyl-a-D-ribofuranose | 22224-41-5 | 99.8% | 462.45 | 25 G
1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs exhibit broad antitumor activity, particularly against indolent lymphoid malignancies. Their anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis.
- Broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
Apexbio Technology LLC Aclidinium Bromide 320345-99-1 10mM (in 1mL DMSO)
Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism
Medchemexpress LLC Sofpironium bromide | 1628106-94-4 | 98.3% | 470.40 | 25 MG
Sofpironium bromide is an anticholinergic agent that has been studied for its use in treating primary axillary hyperhidrosis (PAH). It works by inhibiting M3 muscarinic receptors in the eccrine glands at the application site, thereby reducing sweating. The compound also demonstrates high affinity for M1, M2, M4, and M5 muscarinic receptor subtypes.
- Anticholinergic agent
- Used in the study of primary axillary hyperhidrosis (PAH)
- Reduces sweating by inhibiting M3 muscarinic receptors in eccrine glands at the application site
- Demonstrates high affinity for M1, M2, M4, and M5 muscarinic receptor subtypes
Cayman Chemical N4-benzoyl-CytIdIn 25g
A benzyolated derivative of cytidine; a substrate of UCK1 and UCK2; has been used in the synthesis of 2ʹ-OH protecting groups for solid-phase RNA synthesis and synthetic oligonucleotides for UV light-induced and targeted gene silencing in zebrafish embryos
Medchemexpress LLC 4-(2-Bromoacetyl)benzonitrile | 20099-89-2 | 99.6% | C9H6BrNO | 25G
4-(2-Bromoacetyl)benzonitrile, also known as 4-Cyanophenacyl bromide, is a compound used in the synthesis of STA-5312, a potent and orally active microtubule inhibitor. This product is intended for research use only.
- Can be utilized in the synthesis of STA-5312.
- Appears as an off-white to yellow solid.
- Store at 4°C, protected from light.
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.
- Soluble in DMSO at 100 mg/mL.
Medchemexpress LLC N4-Benzoyl-2 -O-meth 5g
N4-Benzoyl-2 -O-methylcytidine is a natural cytidine nucleoside analog Cytidine analogs have the mechanism of inhibiting DNA methyltransferase (such as Zebularine (HY-13420)) and have potential antimetabolite and antitumor activities[1][2]
Aobchem 1-Benzoyl-4-piperidinecarboxaldehyde | 95% | CAS 120014-29-1 | C13H15NO2 | 250mg
1-Benzoyl-4-piperidinecarboxaldehyde | 95% | CAS 120014-29-1 | C13H15NO2 | 250mg
Aobchem 5-Benzoyl-2-thiophenecarboxaldehyde | 95% | CAS 72157-21-2 | C12H8O2S | 5g
5-Benzoyl-2-thiophenecarboxaldehyde | 95% | CAS 72157-21-2 | C12H8O2S | 5g
Aobchem 5-Benzoyl-2-thiophenecarboxaldehyde | 95% | CAS 72157-21-2 | C12H8O2S | 10g
5-Benzoyl-2-thiophenecarboxaldehyde | 95% | CAS 72157-21-2 | C12H8O2S | 10g
Medchemexpress LLC Demecarium Bromide | 56-94-0 | 50 MG
Demecarium Bromide is a potent cholinesterase inhibitor with an apparent affinity (Kiapp) of 0.15 μM. It is primarily used as a glaucoma agent. This product serves as an analytical standard, suitable for research and analytical applications.
- Potent cholinesterase inhibitor
- Used as a glaucoma agent
- Suitable for research and analytical applications
Apexbio Technology LLC Methylbenactyzine-Bromide
Methylbenactyzine Bromide (CAS No 3166-62-9) is a synthetic anticholinergic agent primarily used in neuromuscular research Originating from studies on muscarinic receptor antagonists this compound targets muscarinic acetylcholine receptors inhibiting neurotransmission in cholinergic pathways Its efficacy is noted within the nanomolar to low micromolar range in in vitro assays making it a valuable tool in pharmacological studies focused on modulating neuronal activity The compound is commonly applied in cell models to explore neurophysiological processes and in animal studies to assess its impact on muscle relaxation and potential therapeutic effects for conditions like muscle spasms Additionally it serves as a reference compound in drug screening programs aimed at identifying new anticholinergic agents Experimental concentrations typically depend on the specific research design allowing for tailored applications across varied experimental settings